ASKEP OSTEOSARKOMA PDF

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Secara morfologik terdapat beberapa jenis osteosarkoma, yang tersering ialah osteosarkoma pada metafisis tulang panjang, primer, intrameduler, dengan osteoblas bergradasi tinggi.

Penyebab osteosarkoma tidak diketahui, namun berbagai agen dan status penyakit dihubungkan dengan perkembangan osteosarjoma ini.

Macroscopically, it manifests as a big, sandy, whitish grey tumor, which is often with bleeding areas and cysts; meanwhile, microscopically it varies.

Pemeriksaan radiologik berperan penting dalam evaluasi awal osteosarkoma. Umumnya tumor tumbuh pada distal femur di bagian metafisis. User Username Password Remember me.

Penyebaran hematogen sering terjadi pada awal penyakit, biasanya ke paru-paru dan tulang. Penyakit ini termasuk keganasan sistem skeletal nonhematopoetik yang tersering dengan distribusi usia bimodal. Early signs and symptoms are not specific, mostly manifests as pain with or without palpable mass.

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Gambaran makroskopik yaitu tumor besar, berpasir, berwarna abu-abu keputihan, dan sering terdapat area perdarahan dan kiste sedangkan gambaran mikroskopik bervariasi. Radiological examination is important in early evaluation of osteosarcoma. A teenager with a painful mass around the knee has to undergo further examination for early detection of osteosarcoma. Gejala awal osteosarkoam spesifik yaitu nyeri dengan atau tanpa teraba massa. Morphologically, there are several types of osteosarcoma.

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Malignant osteoblasts that produce osteoid matrix is the diagnostic tool. Osteosarkoma is defined as a neoplasma in which the osteoid tissue is synthesized by malignant cells. Hematogen metastasis often occurs at the early stage of this disease mostly to lungs and bones.

It belongs to the most frequent nonhemapoietic skeletal malignancy with a bimodal age distribution. Prognosis penyakit ini dipengaruhi oleh ukuran tumor, derajat nekrosis, penyebaran ke korteks dan jaringan lunak, serta adanya metastasis.

OSTEOSARKOMA | Loho | JURNAL BIOMEDIK

Osteoblas maligna yang memroduksi matriks osteoid merupakan gambaran diagnostik. The most frequent type is osteosarcoma in the long bone metaphysis, primary, intramedullary, with high gradation of osteoblasts.

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The prognosis of such cases depends on the tumor size, necrosis degree, dissemination to cortex and soft tissue, and metastasis. Pada kasus usia belasan dengan massa yang nyeri di sekitar lutut perlu dilakukan pemeriksaan lanjut untuk deteksi dini osteosarkoma.

The causes are still unknown, however, a variety of agents and diseases are related to the development of this disease. Osteosarkoma didefinisikan sebagai suatu neoplasma dimana jaringan osteoid disintesis oleh sel ganas.

Most osteosarcoma tumor develop in the distal part of femur in the metaphysis.